I shot a pretty nice 8pt for my part of the world with my 450 on opening day of gun season 2016. He was about 60 yards when I shot him with a factory Hornady 250sst. He ran about 50 yards or so, but was easy to trail. There were pieces of lung along the blood trail - large exit wound. Deer weighed a little under 200lbs. I also shot a doe this year. She was kinda small at 100yds or so. I saw white belly on the ground after the shot. After several years of hunting with the 450, I am still impressed.